Lei Sun Selected Research

Precision Medicine

1/2024	A multidimensional platform of patient-derived tumors identifies drug susceptibilities for clinical lenvatinib resistance.
4/2023	New use for an old drug: quinidine in KCNT1-related epilepsy therapy.
2/2020	An octopus-mimic PEGylated peptide as a specific integrin αvβ3 inhibitor for preventing tumor progression.
1/2020	Surface-modified GVs as nanosized contrast agents for molecular ultrasound imaging of tumor.
1/2019	Genetic association and transcriptome integration identify contributing genes and tissues at cystic fibrosis modifier loci.
1/2018	Tumor-penetrating Peptide Conjugated and Doxorubicin Loaded T1-T2 Dual Mode MRI Contrast Agents Nanoparticles for Tumor Theranostics.
1/2017	A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine)-paclitaxel Polymeric Delivery System for Tumor Theranostics.
10/2016	Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics.

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Lei Sun Research Topics

Disease

168	Neoplasms (Cancer) 05/2024 - 09/2004
60	Inflammation (Inflammations) 04/2024 - 07/2002
59	Infections 05/2024 - 08/2008
25	Neoplasm Metastasis (Metastasis) 03/2024 - 08/2012
23	Fibrosis (Cirrhosis) 04/2024 - 03/2011
23	Obesity 12/2022 - 10/2009
21	Hypoxia (Hypoxemia) 01/2022 - 05/2005
20	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 01/2014
19	Hepatocellular Carcinoma (Hepatoma) 11/2023 - 10/2011
16	Insulin Resistance 02/2024 - 10/2013
16	Body Weight (Weight, Body) 03/2023 - 12/2008
15	Carcinogenesis 03/2024 - 03/2008
15	Wounds and Injuries (Trauma) 10/2023 - 12/2006
15	Acute Lung Injury 01/2020 - 07/2002
14	Lung Neoplasms (Lung Cancer) 04/2024 - 01/2013
14	COVID-19 02/2024 - 01/2020
14	Virus Diseases (Viral Diseases) 03/2023 - 06/2009
14	Schizophrenia (Dementia Praecox) 02/2023 - 05/2014
13	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 01/2013
12	Adenocarcinoma of Lung 10/2023 - 10/2008
12	Atherosclerosis 01/2023 - 04/2015
11	Weight Gain 10/2023 - 05/2014
10	Non-alcoholic Fatty Liver Disease 12/2023 - 02/2018
10	Breast Neoplasms (Breast Cancer) 02/2022 - 02/2010
9	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 01/2017
9	Pain (Aches) 01/2024 - 08/2013
9	Carcinoma (Carcinomatosis) 12/2023 - 09/2008
9	Type 2 Diabetes Mellitus (MODY) 12/2023 - 01/2016
9	Mitochondrial Diseases (Mitochondrial Disease) 11/2023 - 05/2014
9	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 10/2012
9	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 04/2011
8	Lung Injury 03/2024 - 08/2008
8	Sepsis (Septicemia) 01/2022 - 07/2004
8	Ischemia 01/2019 - 10/2006
7	Epilepsy (Aura) 05/2024 - 10/2012
7	Liver Neoplasms (Liver Cancer) 01/2024 - 10/2016
7	Necrosis 11/2023 - 10/2007
7	Thalassemia 11/2023 - 04/2014
7	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2023 - 01/2017
7	Leukemia 10/2022 - 04/2002
7	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2022 - 11/2011
6	Cognitive Dysfunction 04/2024 - 01/2012
6	Spinal Cord Injuries (Spinal Cord Injury) 11/2023 - 06/2012
6	Hemorrhage 10/2023 - 11/2009
6	Pneumonia (Pneumonitis) 01/2023 - 07/2009
6	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 01/2020
6	Adenocarcinoma 01/2023 - 02/2017
6	Lung Diseases (Lung Disease) 04/2022 - 03/2008
6	Colonic Neoplasms (Colon Cancer) 01/2022 - 10/2016
6	Myocardial Infarction 10/2021 - 01/2011

Drug/Important Bio-Agent (IBA)

77	Proteins (Proteins, Gene)FDA Link 04/2024 - 04/2002
37	Biomarkers (Surrogate Marker)IBA 04/2024 - 01/2013
35	CytokinesIBA 03/2024 - 07/2006
20	Messenger RNA (mRNA)IBA 04/2024 - 04/2002
19	Antiviral Agents (Antivirals)IBA 02/2024 - 09/2008
19	MicroRNAs (MicroRNA)IBA 12/2023 - 10/2009
17	RNA (Ribonucleic Acid)IBA 12/2023 - 10/2013
17	LipidsIBA 12/2023 - 06/2009
15	Peptides (Polypeptides)IBA 10/2022 - 02/2012
14	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 02/2010
14	Olanzapine (Zyprexa)FDA Link 01/2022 - 05/2014
13	InterferonsIBA 12/2023 - 06/2009
13	3-carboxamido-4-hydroxynaltrexoneIBA 01/2022 - 11/2018
12	CollagenIBA 04/2024 - 06/2009
12	Interleukin-6 (Interleukin 6)IBA 10/2022 - 09/2009
12	Long Noncoding RNAIBA 04/2022 - 01/2016
11	Therapeutic UsesIBA 09/2023 - 08/2008
11	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 01/2011
11	CateninsIBA 01/2022 - 12/2015
11	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2017 - 10/2006
10	Indicators and Reagents (Reagents)IBA 01/2023 - 09/2004
10	Antipsychotic Agents (Antipsychotics)IBA 01/2022 - 05/2014
9	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 04/2002
9	Cyclophilin AIBA 03/2024 - 12/2010
9	Insulin (Novolin)FDA Link 02/2024 - 10/2013
9	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2024 - 10/2013
9	LipopolysaccharidesIBA 11/2023 - 06/2010
8	Bleomycin (Blenoxane)FDA LinkGeneric 03/2024 - 03/2005
8	Small Interfering RNA (siRNA)IBA 03/2024 - 01/2019
8	AntibodiesIBA 02/2024 - 05/2011
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2024 - 07/2009
8	Phosphotransferases (Kinase)IBA 12/2023 - 10/2007
8	LigandsIBA 01/2023 - 10/2010
8	Paclitaxel (Taxol)FDA LinkGeneric 06/2022 - 10/2008
7	Protein Kinases (Protein Kinase)IBA 03/2024 - 03/2005
7	Interleukin-10 (Interleukin 10)IBA 12/2023 - 07/2009
7	Triglycerides (Triacylglycerol)IBA 03/2023 - 07/2011
7	AntioxidantsIBA 01/2023 - 01/2013
7	Narcotic Antagonists (Opioid Antagonists)IBA 01/2022 - 01/2019
6	AntigensIBA 04/2024 - 08/2017
6	InterleukinsIBA 10/2023 - 06/2016
6	CholesterolIBA 01/2023 - 09/2015
6	Interleukin-8 (Interleukin 8)IBA 05/2022 - 05/2009
6	Oxygen (Dioxygen)IBA 04/2022 - 05/2005

Therapy/Procedure

79	Therapeutics 05/2024 - 05/2007
14	Drug Therapy (Chemotherapy) 04/2024 - 03/2008
13	Immunotherapy 12/2023 - 05/2017
8	Precision Medicine 01/2024 - 10/2016
7	Transplantation 11/2022 - 12/2008
6	Aftercare (After-Treatment) 01/2023 - 04/2013